Constant and continuous drying during pharmaceutical solids production must be guaranteed to seamlessly connect to continuous wet granulation. With the BCD continuous fluid bed dryer, L.B. Bohle now enables the continuous drying of granules for the first time.

Continuously produced wet granules fall gravimetrically into the dryer without any further necessary transport Source: L.B. Bohlesteps and are then dried in a continuous process. The constant conveying of the wet granules from the dryer inlet toward its outlet is achieved by a controllable movement, ensuring gentle and uniform drying.

Back-mixing problems are eliminated and all granules (even in different particle sizes) are dried for the same length of time. Innovative product filters guarantee service lives of days without having to interrupt the continuous granulation process. As a result, there is no loss of quality, even with finely micronized drugs.

The BCD fluid bed dryer is the ideal tool for the continuous manufacturing of high-quality products on a laboratory and production scale. The implementation of process analytical technology for constant in-line determination of the granule moisture content and for feedback control of the process also ensures process and product quality. The BCD can be used within the QbCon 1 laboratory machine for throughputs of 0.25 to 2.5 kg/h or for production sizes up to 25 kg/h.